I have a surprise for you! If you read this post until the very end, you will be among the first to hear about the release of my new book! You will hear about this even before the regular listeners of my Monday night internet radio show.
If you look at the last several posts, I wrote for you, you might see that I am preparing you to be able to take advantage of the information in my upcoming book. In that way, you and your loved ones can create even more wellness, energy, and joy. If you missed this pattern, let’s do a short review.
Short Review of Latest Posts
Following through from my post on the Labyrinth of the Mind, I did a long post on Relieving Stress with the Emotional Freedom Technique (“EFT”/Tapping). What I have found over time is that EFT is an effective technique to shift anything that is stuck (pain, stress, upset, etc.). I want you to have a tool to help you, if you detox on the emotional/mental/spiritual levels.
After those posts, I turned the conversation to healthy eating, with the following posts:
In these posts, I give you my two suggestions for the healthiest eating plans as well as review others with which you might be familiar, telling you why I don’t recommend them.
Then, I wrote the post, Detoxing A-Z for Beginners with RnA ReSet. In that post, I give you support tools and tell you how to use them.
If you and your loved ones have a strong desire to feel good all the time, then please read, “Are You an Addictive Person?” In this post I discuss how people’s habits can easily become “hidden addictions.”
Today’s post will give you additional support for when you improve your health by changing your lifestyle habits, i.e., eating, hydration, exercise, sunlight, and fresh air. Specifically, I’m discussing ReAline. I love to call this my “take out the trash” product.
What Is ReAline?
Here is how I describe ReAline in the eBook I wrote about the product:
“ReAline is a multitasking dietary supplement. It’s a very gentle detoxifier and a unique B vitamin complex that is both food-based and methylated.
ReAline’s formula of B vitamins and amino acids provides the perfect building blocks to enhance and assist the body in detoxifying chemicals, heavy metals, and toxins. Instead of forcing the body with purges or IV chelation, methionine promotes the production of glutathione, the body’s most important antioxidant. Having methionine on hand allows the body to make glutathione as needed.
Methionine and taurine are both sulfur amino acids lending sulfur to the liver’s sulfation detox pathways. The B vitamins in ReAline work synergistically with methionine and magnesium. Four B’s are methylated, allowing the transfer of a methyl group to the liver’s methylation detoxification pathways.
One specific function of methylation is to help break down toxic homocysteine that can cause atherosclerosis. The inclusion of methylated B’s in ReAline became even more important as the MTHFR gene variations were identified. I contend that gene variations are expressed partly because we are deficient in magnesium and many other important nutrients. The rest of the B vitamins in ReAline are food-based, which makes them easily absorbed and effective.
The B’s are essential for supporting neurological health. This becomes even more obvious when we realize that B12, B6, and folate deficiencies are common in children in the autism spectrum and also in the elderly. But there is much more going on. The B vitamins are co-factors in thousands of biochemical processes. They work together, helping cells burn fats and glucose for energy, promoting cell growth and division, maintaining healthy skin and muscle tone, supporting and increasing the rate of metabolism, and enhancing immune and nervous system function, which includes easing stress and improving mood, probably triggered by an increased production of serotonin. The ability of the B vitamins to help reduce anxiety, depression, and PMS is enhanced with the use of magnesium.
Most commercial B vitamins are synthetic and don’t bind properly to receptors on the cell surface. This means doctors are forced to recommend higher and higher doses to try to get the body to respond. However, food-based and methylated B’s are in the active form that the body requires and do not have to be taken in high amounts.
Methionine has 4 major roles in the ReAline formula. Methionine is a building block in the manufacture of all our proteins, including structural, contractile, blood, antibodies, hormones, and enzymes. It is a methyl donor, needed for the production of neurotransmitters, a sulfur donor, and a precursor in the synthesis of other amino acids. Methionine has the ability to inhibit toxic metals from crossing the blood-brain barrier. Methionine is a critical component of tissue development, growth, and tissue repair for all humans at any age.
Taurine is a precursor to GABA, a brain neurotransmitter that calms the central nervous system and can actually help reduce the seizure threshold. It also may help alleviate depression, anxiety, insomnia, and addiction. Taurine also reduces elevated levels of cortisol in the body; helps burn fat; improves insulin sensitivity; increases testosterone production; acts as an antioxidant; enhances heart and brain function; and improves sleep. It also lends sulfur molecules to the body for innumerable tasks.
Even though sulfur is the third most common mineral in the body (after calcium and phosphorous), sulfur’s importance is not commonly acknowledged. However, it is a key component in DNA and protein replication. Sulfur is important for the production of mucous and for the sulfur detoxification pathways in the liver. It also promotes the health of ligaments, cartilage, collagen, and tendons; sulfur deficiency may lead to degeneration of these tissues. Half the amount of sulfur in our body can be found in the muscles, skin, and bones.”
Gentle Detox with ReAline
Many people think that protection from all the toxins in the environment means living the rest of your life in a hermetically sealed suit (and it would be a short life since you couldn’t eat or drink.) Fortunately, there are ways to counteract toxins and pollutants. Your body’s natural detoxification processes exist to deal with the ones we can’t avoid.
ReAline is a very gentle detoxifier. Detoxification can place more stress on an already stressed-out body, so in the past, I’ve focused on transdermal and external detoxification such as Epsom salts baths, clay baths, coffee enemas, gentle saunas, and castor oil packs to avoid detox reactions. [We discussed these in my last post.] I have concerns about internal intestinal purges, liver detoxing, and gall bladder flushes that stir up internal toxins that just migrate to another part of the body and set up residence. Also, flushing out toxins can force minerals out of the body with greatly increased bowel movements and excessive urination. Liver detoxes can release viruses sequestered in the liver before the immune system is ready to handle them.
ReAline contains a combination of B vitamins along with specific amino acids that gently support your body’s ability to detoxify.
Ingredients in ReAline
- L-methionine & L-taurine are sulfur-based amino acids
- L-Methionine is a precursor to glutathione, the body’s own antioxidants
Our ReAline formula may replace several supplements that you have been taking:
- Vitamin B1 (thiamine from Saccharomyces Boulardii) (natural source) – 4mg
- Vitamin B2 ( as Riboflavin 5 phosphate) – 4 mg
- Niacin (from Saccharomyces Cells) – 10 mg
- Vitamin B6 Pyridoxine 5 phosphate – 4 mg
- Folic acid (as Quatrefolic®) – 200 mcg
- Vitamin B12 (as Methylcobalamin) – 250 mcg
- Biotin (from Saccharomyces Cells) – 50 mcg
- L-Methionine (natural source) – 500mg
- L-Taurine (natural source) – 200mg
- Pantothenic Acid (from Saccharomyces Cells) – 6 mg
Other Ingredients: non-GMO Vegetable cellulose (capsule shell), Cellulose, Vegetable Stearate, Silica
Notes on Ingredients
Quatrefolic®, Folate, Folic Acid
If you have questions about Quatrefolic® in our ReAline, please click here to read the manufacturer’s words on Quatrefolic®, Folate, and Folic Acid.
Vitamin B2 (riboflavin) in ReAline can naturally turn urine yellow when your body doesn’t use it all.
ReAline is sugar-free, dairy-free, and gluten-free
MTHFR Gene Variation and Methylated Bs
When customers ask about ReAline, they ask why some of the vitamins are methylated. This information is taken from my ReAline eBook and is very detailed description of the MTHFR gene variation and supplementing with methylated B vitamins:
“When you talk about methylated B vitamins, you have to address the research on the MTHFR enzyme gene mutation and why it’s suddenly become the most talked about mutation in nutritional medicine. As some practitioners are saying, it’s more of a gene variation that has been picked up in genetic testing –not a true mutation.
MTHFR is an enzyme (produced by the MTHFR gene) that adds a methyl group to folic acid (B9) to make it usable by the body as a folate. Vitamin B12 (Methylcobalamin) assists this process as a co-factor.
Folate is an essential nutrient; it is vital for the production and repair of DNA. Methionine is a sulfur amino acid that donates a methyl group to turn folic acid into folate. Methionine is also the building block for several proteins, including glutathione, the body’s most important antioxidant.
The body recycles methionine with the help of an enzyme called methionine synthase, which converts homocysteine into methionine, also utilizing the co-factor vitamin B12 (Methylcobalamin).
In short, homocysteine is a product of protein metabolism and the methionine cycle helps reduce the levels of homocysteine in the body while it creates methionine and allows it to activate folate. Elevated homocysteine is linked to an increased risk of heart attack and stroke in the following way. When protein breaks down, homocysteine is one of the amino acids produced. Homocysteine oxidizes cholesterol, and oxidized cholesterol is the kind that damages blood vessels.
Methionine synthase comes to the rescue because it is the most important enzyme involved in breaking down and getting rid of homocysteine. Most relevant to our discussion is that methionine synthase is magnesium-dependent. If you are magnesium-deficient, simply eating protein will produce homocysteine, which creates oxidized cholesterol and potentially more blood vessel damage.
But let’s not wait for homocysteine to become elevated, let’s prevent it from forming. If you have the specific nutrient co-factors that I mentioned – magnesium and B vitamins – to digest protein optimally, you won’t build up homocysteine in the first place.
In the Magnesium Miracle, I say that elevated homocysteine (hyperhomocysteinemia) is high on the list of risk factors for heart disease and serves as an even stronger marker than high cholesterol for heart disease and blood clotting disorders. However, it is not on a standard blood test panel for heart disease. This is probably because there is no drug treatment to lower homocysteine, only nutrient treatments –B vitamins and magnesium.
I make the case that the more relevant marker for heart disease may be low magnesium, since the major enzyme involved in homocysteine metabolism, as I’ve already mentioned, is magnesium-dependent. When magnesium and the methylated B vitamins –vitamin B2, B6, B12, and folate –are deficient, the body is not able to properly digest dietary protein.
Magnesium and the B vitamins were readily available in the typical diet a hundred years ago. Now that they are deficient or absent, homocysteine levels are rising, resulting in heart disease. It’s not just homocysteine that is controlled by methionine; the methyl group in methionine that is transferred to make folate is necessary for DNA methylation to occur.
Perhaps not having enough absorbable magnesium and methylated B vitamins is causing this drastic shift in gene function, resulting in MTHFR mutations. Magnesium and the B vitamins are the most important co-factors and epigenetic factors in human metabolism that have the ability to turn genes off and on.
For a drug-based culture, giving this much power to nutrients may seem absurd. However, I’d like to point out that our basic body structure is not that complex. Take the fact that almost 99% of the human body is made up of a mere six elements: oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus. Only1% is composed of potassium, sulfur, sodium, chlorine, and magnesium. The remaining fraction consists of all the other elements in the periodic table. So, yes, a handful of nutrients can be all-powerful!
I’ve said that the MTHFR variations may be triggered because of magnesium and B vitamin deficiencies, but there’s more to the story. When the powerful toxin acetaldehyde builds up in the body as a toxic byproduct of yeast metabolism, it can shut down the function of methionine synthase. Shutting down this powerful enzyme means that methionine isn’t created from homocysteine and its methyl group is not available to create folate to make and repair our DNA.
Acetaldehyde is created in measurable amounts when yeast overgrows in the intestines. I’ve talked about the damage caused by acetaldehyde for decades and listed yeast overgrowth and mineral deficiency as the main factors in chronic disease. Even though more people are catching on and acknowledging the effects of yeast overgrowth, they don’t understand how deep the problem goes.
Acetaldehyde is a toxic byproduct of not just yeast but also of alcohol, car exhaust, and cigarette smoke. I’ve written about it extensively in my eBook, ReSet the Yeast Connection. Following this program will reduce yeast overgrowth and the damage caused by its 178 toxins, one of which is acetaldehyde. Part of that program includes taking ReMag because magnesium empowers aldehyde dehydrogenase to help breakdown and eliminate acetaldehyde. Molybdenum, found in our ReMyte, is also an acetaldehyde buster.
The MTHFR variations were only recently recognized as an offshoot of the Human Genome Project, and some sources say that a whopping 30-50% of the population may be affected. Such a high level of mutation does not occur overnight and opens a Pandora’s box of questions. That’s why I choose to side with the practitioners calling MTHFR a genetic variation. Were these variations always there? Probably.
If we examined blood from 50 years ago would the same level of variation exist? Are the variations expressing themselves because of the epigenetic function of magnesium and B vitamin deficiency, and increased levels of acetaldehyde, heavy metal, and chemical toxicity in our environment? Will we ever know the answers?
Epigenetics defines changes in gene expression that are not caused by changes or mutations in the DNA itself but by factors in the environment. Of great importance are systems that turn genes on and off: DNA methylation and histone modification. If one or more of these systems is disrupted, inappropriate expression of genes can occur.
*DNA methylation is disrupted by the gene variations of the MTHFR gene that do not produce enough methyl groups to do their job.
*Histones are a family of basic proteins that associate with DNA in the nucleus of cells. Nuclear DNA does not appear in free linear strands; it is highly condensed and wrapped around histones in order to fit inside of the nucleus and take part in the formation of chromosomes. A nucleosome is a basic unit of DNA packaging in cells consisting of a segment of DNA wound in sequence around eight histone protein cores.
Here’s where the interesting part comes in. Specific binding sites for magnesium and calcium ions exist within the nucleosome and play a critical role in nucleosome stability. Other ions, such as zinc, iron, copper, and manganese have little or no effect on the stability of histone-DNA interactions.
If, as I’ve laid out, magnesium and the B vitamins, especially methylated B’s, are so important, doesn’t it make sense to supplement with highly absorbed magnesium like ReMag and low potency methylated and food based B vitamins, and amino acids like the ones in ReAline, before consigning huge groups of people to a diagnosis of a MTHFR genetic variation? Therapies for MTHFR variation already include methylated B6, folate, and Methylcobalamin, but are usually missing magnesium and methionine. Let me repeat! Therapies for MTHFR variation are usually missing magnesium and methionine.”
Detailed Description of Nutrients in ReAline
A coenzyme required for the breakdown of sugars (carbs) and amino acids (protein), thiamine plays a central role in the release of energy from carbohydrates. It is involved in RNA and DNA production, as well as nerve function. Its active form is a coenzyme called thiamine pyrophosphate (TPP), which takes part in the conversion of pyruvate toacetyl coenzyme A (CoA) in metabolism.
This vitamin is a vital component of two coenzymes called FAD (flavin adenine dinucleotide) and FMN (flavin mononucleotide), which are critical for the metabolism of carbohydrates, fats, and proteins into energy. Riboflavin is involved in release of energy in the electron transport chain, the Krebs cycle, as well as the catabolism of fatty acids (beta oxidation).
This vitamin is the precursor to enzymes needed in many metabolic processes which also require magnesium, zinc, and manganese. These minerals are found in ReMag and ReMyte. Niacin is composed of two structures: nicotinic acid and nicotinamide. Both play an important role in energy transfer reactions in the metabolism of glucose, fat, and alcohol. Both niacin and riboflavin play a role in the Krebs Cycle.
B5 –Pantothenic acid
This B vitamin is a precursor to Coenzyme A (CoA) and therefore plays a crucial role in the metabolism of many compounds. CoA is involved in the oxidation of fatty acids and carbohydrates and the synthesis of amino acids, fatty acids, ketone bodies, cholesterol, phospholipids, steroid hormones, neurotransmitters (such as acetylcholine), and antibodies. CoA facilitates the initiation of the Krebs cycle, which I talk about nonstop because magnesium is required in 6 of the 8 steps of the Krebs cycle.
B6 is a complex having 6 different components. The active methylated form, pyridoxal 5′-phosphate (PLP), serves as a co-factor in many enzyme reactions mainly in amino acid metabolism, including the biosynthesis of neurotransmitters.
This vitamin plays a key role in the metabolism of lipids, proteins, and carbohydrates. It is a critical co-enzyme involved in the synthesis of fatty acids, gluconeogenesis, the metabolism of several amino acids (especially leucine), and cholesterol.
I talked about folate earlier when discussing the MTHFR genetic mutations. Folate has a methyl group and is a precursor necessary to make, repair, and methylate DNA. It is especially important in pregnancy and infancy to aid rapid cell division and growth. Folate acts as a co-enzyme in the form of tetrahydrofolate( THF), which is involved in the transfer of single-carbon units in the metabolism of nucleic acids and amino acids. THF is needed for normal cell division. Folate also aids in the production of red blood cells.
This is a vitamin coenzyme, which is a non-protein compound that is necessary for the functioning of an enzyme. B12 is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid metabolism and amino acid metabolism. Vitamin B12 is involved in the cellular metabolism of carbohydrates, proteins, and lipids. It is essential in the production of blood cells in bone marrow, and for nerve sheaths and proteins. Methylcobalamin is the form of B12 in ReAline.
Taurine is one of the most abundant amino acids in the body. It is found in the central nervous system, skeletal muscle, and is very concentrated in the brain and heart. It is synthesized from the amino acids, methionine and cysteine, in conjunction with vitamin B6. All three are sulfur amino acids.
Taurine modulates and can even inhibit neurotransmitters in the brain. It is a critical neuroinhibitory neurotransmitter involved in calming the nervous system. In this regard, there have been reports on the benefits of taurine supplementation for epileptics. It has also been found to control motor tics, such as uncontrollable facial twitches. Taurine’s effectiveness in epilepsy has been limited by its poor ability to cross the blood-brain barrier.
Taurine can even protect us from fluorine toxicity according to current animal research. However, taurine concentration in the brain declines with age. Thus, taurine’s ability to protect against environmental toxins, reduce brain inflammation, and stimulate neuron formation also declines with age and should be supplemented.
In Japan, taurine therapy is used in the treatment of ischemic heart disease. Low taurine and magnesium levels have been found in patients after heart attacks. Like magnesium, taurine affects cell membrane electrical excitability by normalizing potassium flow in and out of heart muscle cells. Both supplements decrease the tendency to develop potentially lethal abnormal heart arrhythmias after heart attacks. People with congestive heart failure have also responded to taurine supplementation with improved cardiac and respiratory function. Magnesium does the same.
Another role played by taurine is maintaining the correct composition of bile and maintaining the solubility of cholesterol. It has been found to have an effect on blood sugar levels similar to that of insulin. Taurine helps to stabilize cell membranes and seems to have some antioxidant and detoxifying activity. It helps the movement of potassium, sodium, calcium, and magnesium in and out of cells, which helps generate nerve impulses.
Taurine is necessary for the chemical reactions that produce normal vision, and deficiencies are associated with retinal degeneration. Besides protecting the retina, taurine may help prevent and possibly reverse age-related cataracts. Low levels of taurine and other sulfur containing amino acids are associated with high blood pressure, and taurine supplements have been shown to lower blood pressure in some studies. Other possible uses for taurine supplementation include eye disease, cirrhosis, depression, and male infertility due to low sperm motility and hypertension. Possible symptoms of toxicity include diarrhea and peptic ulcers.
I am most interested in methionine for its ability to make glutathione, but it does so much more. I’ve already noted earlier that homocysteine is made from methionine and then recycled back into methionine. It can also be converted into cysteine (another precursor to glutathione) with the aid of folate, vitamin B6, and vitaminB12. Without these B vitamins, homocysteine builds up and is a factor in heart disease.
Methionine is an intermediate in the biosynthesis of two other amino acids and several phospholipids: carnitine, taurine, lecithin, phosphatidylcholine, and other phospholipids.
ReAline contains those B vitamins in methylated form as well as methionine. Not only does ReAline help metabolize homocysteine so that it does not build up in the body, it also acts as a gentle detoxifier.
Methionine is an essential amino acid, which means it cannot be manufactured in the body from other components. It needs to be a part of our diet. It helps with the breakdown of fats and also prevents a buildup of fat in the liver and arteries. It detoxifies heavy metal toxins such as lead, cadmium, and mercury by binding them and aiding in their excretion from the body. It helps diminish muscle weakness, prevents brittle hair, and protects against radiation.
Methionine is a sulfur amino acid and by utilizing its supply of sulfur, it improves the tone and texture of the skin, strengthens nails, and conditions the hair. The mineral sulfur also protects the cells from airborne pollutants, such as smog, slows down the aging process in the cells, and is involved with the production of protein.
Methionine has a special relationship with selenium and zinc. It is required for the absorption, transportation, and bioavailability of these minerals in the body.
Methionine can help fatigue and may be useful in some cases of allergy because it reduces histamine release. Like magnesium, methionine is a histamine inhibitor! It has also been used in the treatment of rheumatic fever and toxemia resulting from pregnancy. Toxemia of pregnancy is another magnesium deficiency condition.
As you can see, the ingredients I chose for ReAline are geared to gentle detoxification on all levels. If you wish to read the complete ReAline eBook, click here to download a free PDF.
In the meantime, here is how to start using ReAline:
- Week One – Take one ReAline with breakfast.
- Week Two Onward – Take one ReAline with breakfast and one ReAline with lunch
The Big Reveal
I’m so excited. You are among the first readers/customers to learn that I am releasing my next book on August 22,Sugar without the Icing! This book is a culmination of decades of research, working with patients and customers, and refining my understanding of how detrimental sugar is to your health. I nearly sacrificed my entire career to get this information out, and I am so glad that other doctors and science has caught up with me. Stay tuned for announcements on my Monday night internet radio show. Link for information on the show appears above.
Dr. Carolyn Dean